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Vasohibin 1 (VASH1)

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Vasohibin 1 (VASH1)
CCC G904
HGNC 19964
MGI 2442543
PubMed 23056314
RGD 1564082
UniProt Q7L8A9
Wiki VASH1
Vasohibin protein contains a cluster of basic amino acids in its C terminus and no classic secretion signal sequence. Vasohibin expression was robust between embryonic weeks 6 to 12 in heart, brain, kidney, lung, skeletal muscle, and whole embryo. Immunohistochemical analysis detected vasohibin at the endothelial layer of placenta and brain.
The deduced protein contains 365 amino acids. RT-PCR ELISA detected intermediate expression in adult heart, brain, lung, liver, kidney, ovary, and spinal cord, as well as in fetal brain. Lower expression was detected in skeletal muscle, testis, pancreas, and fetal liver, and little to no expression was detected in spleen. All specific adult brain regions examined showed low to moderate expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasohibin 1 (VASH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasohibin 1 (VASH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasohibin 1 (VASH1) Polyclonal Antibody Customized Service Offer
Assay Kits SEG904Hu ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasohibin 1 (VASH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasohibin 1 (VASH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasohibin 1 (VASH1) Polyclonal Antibody Customized Service Offer
Assay Kits SEG904Mu ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasohibin 1 (VASH1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasohibin 1 (VASH1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasohibin 1 (VASH1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasohibin 1 (VASH1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasohibin 1 (VASH1) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis."J. Clin. Invest. 114:898-907(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Gene regulation of a novel angiogenesis inhibitor, vasohibin, in endothelial cells."Biochem. Biophys. Res. Commun. 327:700-706(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Multiple processing forms and their biological activities of a novel angiogenesis inhibitor vasohibin."Biochem. Biophys. Res. Commun. 342:640-646(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Vasohibin prevents arterial neointimal formation through angiogenesis inhibition."Biochem. Biophys. Res. Commun. 345:919-925(2006) [PubMed] [Europe PMC] [Abstract]