Ubiquinol Cytochrome C Reductase Complex III Subunit VII (UQCRQ)

UQCRQ encodes a ubiquinone-binding protein of low molecular mass. This protein is a small core-associated protein and a subunit of ubiquinol-cytochrome c reductase complex III, which is part of the mitochondrial respiratory chain.Ubiquinone is an essential component of the mitochondrial electron transfer system. UQCRQ is a ubiquinone-binding protein localized to the cytochrome bc1 region of the mitochondrial respiratory chain.

The deduced 110-amino acid protein has a relatively hydrophobic and basic N-terminal region, an aspartic acid-rich middle region, and a glutamic acid- and lysine-rich C-terminal region.The International Radiation Hybrid Mapping consortium mapped the UQCRQ gene to chromosome 5.