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UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15)

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UGT2B8; HLUG4; UDPGTh-3; UDP-glucuronosyltransferase 2B8

UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15)
CCC G935
HGNC 12546
MGI 3576100
PubMed 9295060
RGD 620895
UniProt P54855
Wiki UGT2B15
The UGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B8 demonstrates reactivity with estriol.the cDNA corresponding to UGT2B8 is 2,094 bp and encodes a protein of 523 amino acids, including a 16-amino acid leader sequence, and has an untranslated 3-prime region of 525 bp.
The steroid-metabolizing isoforms of UDP-glucuronosyltransferase are encoded by multiple genes. By fluorescence in situ hybridization with a YAC containing all 3 genes, Monaghan et al. (1994) localized UGT2B4, UGT2B9, and UGT2B15 to 4q13. They provisionally ordered the genes as UGT2B9--UGT2B4--UGT2B15.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) CLIA Kit Customized Service Offer
n/a ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B15 (UGT2B15) ELISA Kit Customized Service Offer
  1. "Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms."Biochemistry 32:10648-10657(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates."Drug Metab. Dispos. 22:799-805(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene."Pharmacogenetics 7:317-325(1997) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  6. "Characterization and primary sequence of a human hepatic microsomal estriol UDPglucuronosyltransferase."Arch. Biochem. Biophys. 281:170-175(1990) [PubMed] [Europe PMC] [Abstract]
  7. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "A major genotype in UDP-glucuronosyltransferase 2B15."Drug Metab. Pharmacokinet. 17:164-166(2002) [PubMed] [Europe PMC] [Abstract]