UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17)
[Edit]C19-steroid-specific UDP-glucuronosyltransferase
-96936.jpg)
UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones.
Beaulieu et al. (1996) cloned the cDNA corresponding to a novel UGT, termed UGT2B17, from a human prostate cDNA library. Sequence analysis predicted that the UGT2B17 gene encodes a 530-amino acid polypeptide with an 8-amino acid signal sequence and a single membrane-spanning domain. The amino acid sequence of UGT2B17 is 94% identical to that of UGT2B15. RT-PCR analysis revealed that UGT2B17 is expressed in various tissues, including liver, testis, uterus, mammary gland, and prostate. cell line.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B17 (UGT2B17) | ELISA Kit Customized Service Offer |
- "Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids."J. Biol. Chem. 271:22855-22862(1996) [PubMed] [Europe PMC] [Abstract]
- "Chromosomal localization, structure, and regulation of the UGT2B17 gene, encoding a C19 steroid metabolizing enzyme."DNA Cell Biol. 16:1143-1154(1997) [PubMed] [Europe PMC] [Abstract]
- "Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis." Am. J. Hum. Genet. 83:663-674(2008) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]