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Interferon Alpha 14 (IFNa14)

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LEIF2H; LeIF H; Interferon alpha-H; Interferon lambda-2-H

Interferon Alpha 14 (IFNa14)
CCC G969
HGNC 5420
PubMed 1385305
UniProt P01570
Wiki IFNA14

Lawn et al. (1981) identified the INFA14 gene, which they designated LEIF2H. The deduced protein contains 189 amino acids.Lawn et al. (1981) determined that the coding region of the IFNA14 gene is contained within a single exon. The 5-prime upstream region contains a TATTTAA box.

The IFNA14 gene was positioned in the cluster of interferon genes on 9p22 by deletion mapping (Olopade et al., 1992) Lawn et al. (1981) determined that the IFNA14 and IFNA17 genes are 12 kb apart.

Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. IFNs belong to the large class of glycoproteins known as cytokines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins APG969Hu01 Active Interferon Alpha 14 (IFNa14) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Interferon Alpha 14 (IFNa14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Alpha 14 (IFNa14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Alpha 14 (IFNa14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Alpha 14 (IFNa14) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG969Mu01 Recombinant Interferon Alpha 14 (IFNa14) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Interferon Alpha 14 (IFNa14) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Alpha 14 (IFNa14) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Alpha 14 (IFNa14) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Alpha 14 (IFNa14) ELISA Kit Customized Service Offer
  1. "The structure of eight distinct cloned human leukocyte interferon cDNAs."Nature 290:20-26(1981) [PubMed] [Europe PMC] [Abstract]
  2. "DNA sequence of two closely linked human leukocyte interferon genes."Science 212:1159-1162(1981) [PubMed] [Europe PMC] [Abstract]
  3. "Structural relationship of human interferon alpha genes and pseudogenes."J. Mol. Biol. 185:227-260(1985) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Purification and characterization of multiple components of human lymphoblastoid interferon-alpha."J. Biol. Chem. 267:15210-15216(1992) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes."Biochem. J. 329:295-302(1998) [PubMed] [Europe PMC] [Abstract]
  8. "Identification of glycosylated subtypes of interferon-alpha produced by human leukocytes."Biosci. Biotechnol. Biochem. 58:1714-1715(1994) [PubMed] [Europe PMC] [Abstract]
  9. "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population."J. Interferon Cytokine Res. 16:853-859(1996) [PubMed] [Europe PMC] [Abstract]