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Interferon Alpha 13 (IFNa13)

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LeIF D; Interferon alpha-D

Interferon Alpha 13 (IFNa13)
CCC G970
HGNC 5419
MGI 107659
PubMed 19258923
RGD 1561246
UniProt P01562
Wiki IFNA13
The IFNA13 gene was positioned in the cluster of interferon genes on 9p22 by deletion mapping. Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens—such as viruses, bacteria, or parasites—or tumor cells. IFNs belong to the large class of glycoproteins known as cytokines. Although they are named after their ability to "interfere" with viral replication within host cells, IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes; and they increase the ability of uninfected host cells to resist new infection by virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins APG970Hu01 Active Interferon Alpha 13 (IFNa13) Cell culture; Activity Assays.
EPG970Hu61 Eukaryotic Interferon Alpha 13 (IFNa13) Positive Control; Immunogen; SDS-PAGE; WB.
APG970Hu61 Active Interferon Alpha 13 (IFNa13) Cell culture; Activity Assays.
Antibodies n/a Monoclonal Antibody to Interferon Alpha 13 (IFNa13) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Alpha 13 (IFNa13) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Alpha 13 (IFNa13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Alpha 13 (IFNa13) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG970Mu01 Recombinant Interferon Alpha 13 (IFNa13) Positive Control; Immunogen; SDS-PAGE; WB.
EPG970Mu61 Eukaryotic Interferon Alpha 13 (IFNa13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG970Mu01 Polyclonal Antibody to Interferon Alpha 13 (IFNa13) WB; IHC; ICC; IP.
LAG970Mu71 Biotin-Linked Polyclonal Antibody to Interferon Alpha 13 (IFNa13) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Interferon Alpha 13 (IFNa13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Alpha 13 (IFNa13) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG970Ra01 Recombinant Interferon Alpha 13 (IFNa13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAG970Ra21 Monoclonal Antibody to Interferon Alpha 13 (IFNa13) WB; IHC; ICC; IP.
PAG970Ra01 Polyclonal Antibody to Interferon Alpha 13 (IFNa13) WB; IHC; ICC; IP.
Assay Kits SCG970Ra CLIA Kit for Interferon Alpha 13 (IFNa13) Chemiluminescent immunoassay for Antigen Detection.
SEG970Ra ELISA Kit for Interferon Alpha 13 (IFNa13) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The nucleotide sequence of a cloned human leukocyte interferon cDNA."Gene 10:1-10(1980) [PubMed] [Europe PMC] [Abstract]
  2. "Human leukocyte and fibroblast interferons are structurally related."Nature 285:547-549(1980) [PubMed] [Europe PMC] [Abstract]
  3. "The structure of eight distinct cloned human leukocyte interferon cDNAs."Nature 290:20-26(1981) [PubMed] [Europe PMC] [Abstract]
  4. "Two non-allelic human interferon alpha genes with identical coding regions."EMBO J. 3:1809-1812(1984) [PubMed] [Europe PMC] [Abstract]
  5. "Structural relationship of human interferon alpha genes and pseudogenes."J. Mol. Biol. 185:227-260(1985) [PubMed] [Europe PMC] [Abstract]
  6. "Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides."Mol. Cell. Biol. 5:768-779(1985) [PubMed] [Europe PMC] [Abstract]
  7. "Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-alpha 1 mRNA."Med. Mol. Morphol. 43:145-157(2010) [PubMed] [Europe PMC] [Abstract]
  8. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  10. "Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli."Nucleic Acids Res. 11:5661-5669(1983) [PubMed] [Europe PMC] [Abstract]
  11. "Purification and characterization of multiple components of human lymphoblastoid interferon-alpha."J. Biol. Chem. 267:15210-15216(1992) [PubMed] [Europe PMC] [Abstract]
  12. "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes."Biochem. J. 329:295-302(1998) [PubMed] [Europe PMC] [Abstract]
  13. "IFN-alpha-1a gene is the major variant in the North American population."J. Interferon Cytokine Res. 20:763-768(2000) [PubMed] [Europe PMC] [Abstract]
  14. "Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus."J. Mol. Med. 90:837-846(2012) [PubMed] [Europe PMC] [Abstract]