Thyroid Hormone Receptor Interactor 11 (TRIP11)
[Edit]CEV14; GMAP-210; TRIP230; Golgi-associated microtubule-binding protein 210; Clonal evolution-related gene on chromosome 14 protein
TRIP11 was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.
TRIP11 interacted with rat Thrb only in the presence of thyroid hormone. It also showed a ligand-dependent interaction with RXR-alpha (RXRA), but did not interact with the glucocorticoid receptor (NR3C1) under any condition.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyroid Hormone Receptor Interactor 11 (TRIP11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyroid Hormone Receptor Interactor 11 (TRIP11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Thyroid Hormone Receptor Interactor 11 (TRIP11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Thyroid Hormone Receptor Interactor 11 (TRIP11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Thyroid Hormone Receptor Interactor 11 (TRIP11) | ELISA Kit Customized Service Offer |
- "A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein."Proc. Natl. Acad. Sci. U.S.A. 94:9040-9045(1997) [PubMed] [Europe PMC] [Abstract]
- "GMAP-210, a cis-Golgi network-associated protein, is a minus end microtubule-binding protein."J. Cell Biol. 145:83-98(1999) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Fusion of the platelet-derived growth factor receptor beta to a novel gene CEV14 in acute myelogenous leukemia after clonal evolution."Blood 90:4271-4277(1997) [PubMed] [Europe PMC] [Abstract]
- "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor."Mol. Endocrinol. 9:243-254(1995) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
- "Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210."N. Engl. J. Med. 362:206-216(2010) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome." Nature 456:66-72(2008) [PubMed] [Europe PMC] [Abstract]