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Thyroid Hormone Receptor Interactor 10 (TRIP10)

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STP; CIP4; HSTP; STOT; Salt tolerant protein; Cdc42-Interacting Protein; Protein Felic

Thyroid Hormone Receptor Interactor 10 (TRIP10)
CCC H001
HGNC 12304
MGI 2146901
PubMed 9210375
RGD 621145
UniProt Q15642
Wiki TRIP10
TRIP10 interacted with rat Thrb only in the presence of thyroid hormone. It also showed a ligand-dependent interaction with RXR-alpha (RXRA), but did not interact with the glucocorticoid receptor (NR3C1) under any condition. TRIP10 contains a Src homology-3 (SH3) domain and shows sequence similarity to a Xenopus fyn homolog and chicken src. Northern blot analysis detected a 2.6-kb TRIP10 transcript in several tissues, with highest expression in skeletal muscle.The predicted 545-amino acid CIP4 protein contains an N-terminal domain that bears resemblance to the nonkinase domain of the FER and Fes/Fps family of tyrosine kinases, and a C-terminal SH3 domain. In addition, CIP4 shares sequence similarity with a number of proteins that have roles in regulating the actin cytoskeleton.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thyroid Hormone Receptor Interactor 10 (TRIP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thyroid Hormone Receptor Interactor 10 (TRIP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Thyroid Hormone Receptor Interactor 10 (TRIP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Thyroid Hormone Receptor Interactor 10 (TRIP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Thyroid Hormone Receptor Interactor 10 (TRIP10) ELISA Kit Customized Service Offer
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  3. "Splicing variant of Cdc42 interacting protein-4 disrupts beta-catenin-mediated cell-cell adhesion: expression and function in renal cell carcinoma."Biochem. Biophys. Res. Commun. 339:1083-1088(2006) [PubMed] [Europe PMC] [Abstract]
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  7. "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor."Mol. Endocrinol. 9:243-254(1995) [PubMed] [Europe PMC] [Abstract]
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  9. "Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules."J. Biol. Chem. 275:7854-7861(2000) [PubMed] [Europe PMC] [Abstract]
  10. "Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages."J. Cell Sci. 113:4165-4176(2000) [PubMed] [Europe PMC] [Abstract]
  11. "Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor in the setting of DNA damage."Cancer Res. 61:8022-8031(2001) [PubMed] [Europe PMC] [Abstract]
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  13. "Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup."Blood 101:2804-2809(2003) [PubMed] [Europe PMC] [Abstract]
  14. "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease."Proc. Natl. Acad. Sci. U.S.A. 100:2712-2717(2003) [PubMed] [Europe PMC] [Abstract]
  15. "AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus."Mol. Biol. Cell 15:2771-2781(2004) [PubMed] [Europe PMC] [Abstract]
  16. "Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins."Dev. Cell 9:791-804(2005) [PubMed] [Europe PMC] [Abstract]
  17. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  18. "Regulation of FasL expression: a SH3 domain containing protein family involved in the lysosomal association of FasL."Cell. Signal. 18:1327-1337(2006) [PubMed] [Europe PMC] [Abstract]
  19. "The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics."Exp. Cell Res. 312:2180-2194(2006) [PubMed] [Europe PMC] [Abstract]
  20. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  21. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  22. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  23. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  24. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  25. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  26. "Solution structure of the SH3 domain of the CDC42-interacting protein 4."Submitted (NOV-2005) to the PDB data bank
  27. "Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis." Cell 129:761-772(2007) [PubMed] [Europe PMC] [Abstract]
  28. "The NMR structure of the TC10- and Cdc42-interacting domain of CIP4."J. Biomol. NMR 44:113-118(2009) [PubMed] [Europe PMC] [Abstract]