TLN2 encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.
The deduced 2,532-amino acid protein contains a FERM domain. In TLN1, the FERM domain binds the cytodomains of beta-1 and beta-3 integrins, as well as to F-actin and other proteins. TLN2 shares 74% identity with TLN1, and the N- and C-terminal regions of TLN2 are highly conserved across species.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH015Hu01 | Recombinant Talin 2 (TLN2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAH015Hu01 | Polyclonal Antibody to Talin 2 (TLN2) | WB; IHC; ICC; IP. |
MAH015Hu21 | Monoclonal Antibody to Talin 2 (TLN2) | WB; IHC; ICC; IP. | |
Assay Kits | SEH015Hu | ELISA Kit for Talin 2 (TLN2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Talin 2 (TLN2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Talin 2 (TLN2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Talin 2 (TLN2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEH015Mu | ELISA Kit for Talin 2 (TLN2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Talin 2 (TLN2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Talin 2 (TLN2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Talin 2 (TLN2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEH015Ra | ELISA Kit for Talin 2 (TLN2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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