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Sarcolemma Associated Protein (SLMAP)

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SLAP; Sarcolemmal-Associated Protein

Sarcolemma Associated Protein (SLMAP)
CCC H165
HGNC 16643
MGI 1933549
PubMed 9405447
RGD 1307674
UniProt Q14BN4
Wiki SLMAP
Sarcolemmal membrane-associated protein is a protein encoded by the SLMAP gene. Three alternately spliced isoforms, termed SLAP1, SLAP2, and SLAP3, differing at their 5-prime ends, were identified. The 3 cDNAs predicted proteins of 322, 402, and 639 amino acids, with predicted masses of 37, 46, and 74 kD, respectively. Each of the predicted proteins contained a putative transmembrane domain at its carboxy-terminal tail and 2 potential leucine zipper motifs. SLAP showed extended low-level homology with myosins and other coiled-coil proteins. Northern blot analysis of rabbit tissues revealed 3 mRNAs of 5.9, 4.5, and 3.5 kb, each with a distinct pattern of expression. Immunostaining of rat heart tissue sections demonstrated that SLAP had a reticular pattern of expression in the sarcolemma.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sarcolemma Associated Protein (SLMAP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sarcolemma Associated Protein (SLMAP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sarcolemma Associated Protein (SLMAP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sarcolemma Associated Protein (SLMAP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sarcolemma Associated Protein (SLMAP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sarcolemma Associated Protein (SLMAP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sarcolemma Associated Protein (SLMAP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sarcolemma Associated Protein (SLMAP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sarcolemma Associated Protein (SLMAP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sarcolemma Associated Protein (SLMAP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sarcolemma Associated Protein (SLMAP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sarcolemma Associated Protein (SLMAP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sarcolemma Associated Protein (SLMAP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sarcolemma Associated Protein (SLMAP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sarcolemma Associated Protein (SLMAP) ELISA Kit Customized Service Offer
  1. "Alternative splicing, expression, and genomic structure of the 3' region of the gene encoding the sarcolemmal-associated proteins (SLAPs) defines a novel class of coiled-coil tail-anchored membrane proteins."J. Biol. Chem. 275:38474-38481(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]