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Remodeling And Spacing Factor 1 (RSF1)

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HBXAP; RSF-1; XAP8; p325; Hepatitis B Virus X Associated Protein; HBV pX-associated protein 8; p325 subunit of RSF chromatin-remodeling complex

Remodeling And Spacing Factor 1 (RSF1)
CCC H206
HGNC 18118
MGI 2682305
PubMed 24566868
RGD 1311245
UniProt Q96T23
Wiki RSF1
HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H. It contains a PHD finger and 2 nuclear localization signals. RNA dot blot analysis of 50 different tissues detected ubiquitous expression of HBXAP, with highest expression in adrenal and pituitary glands, and lowest expression in skeletal muscle. SDS-PAGE indicated that in vitro translated HBXAP had an apparent molecular mass of about 240 kD. Western blot analysis detected endogenous HBXAP in 3 liver-derived cell lines. Endogenous HBXAP and epitope-tagged HBXAP expressed in COS-1 cells localized in nuclei, with no staining in the cytoplasm and nucleolar structures.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Remodeling And Spacing Factor 1 (RSF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Remodeling And Spacing Factor 1 (RSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Remodeling And Spacing Factor 1 (RSF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Remodeling And Spacing Factor 1 (RSF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Remodeling And Spacing Factor 1 (RSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Remodeling And Spacing Factor 1 (RSF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Remodeling And Spacing Factor 1 (RSF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Remodeling And Spacing Factor 1 (RSF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Remodeling And Spacing Factor 1 (RSF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Remodeling And Spacing Factor 1 (RSF1) ELISA Kit Customized Service Offer
  1. "HBXAP, a novel PHD-finger protein, possesses transcription repression activity."Genomics 79:523-529(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription."J. Biol. Chem. 277:9982-9988(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Functional analysis of the subunits of the chromatin assembly factor RSF."Mol. Cell. Biol. 23:6759-6768(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  9. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]