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Regulatory Factor X 6 (RFX6)

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RFXDC1; Regulatory Factor X Domain Containing 1

Regulatory Factor X 6 (RFX6)
CCC H227
HGNC 21478
MGI 2445208
PubMed 20148032
RGD 1307491
UniProt Q8HWS3
Wiki RFX6
RFX6 is a member of the regulatory factor X (RFX) family of transcription factors. The deduced 928-amino acid protein is a member of the winged helix family of DNA-binding proteins with high similarity over the DBDs and highest overall similarity to RFX4.
RFX6 contains a winged helix region, predicted to interact with the major groove of DNA, and a conserved helix H3 predicted to interact with the minor groove. EST database analysis showed expression of RFX6 primarily in pancreas with lower expression in liver, which was confirmed by analysis of mouse SAGE libraries. RFX6 interacted with RFX family members RFX2 and RFX3, in addition to interactions with DTX1, DTX2 , FHL3 , CCNK, and SS18L1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Regulatory Factor X 6 (RFX6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Regulatory Factor X 6 (RFX6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Regulatory Factor X 6 (RFX6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Regulatory Factor X 6 (RFX6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Regulatory Factor X 6 (RFX6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Regulatory Factor X 6 (RFX6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Regulatory Factor X 6 (RFX6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Regulatory Factor X 6 (RFX6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Regulatory Factor X 6 (RFX6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Regulatory Factor X 6 (RFX6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Regulatory Factor X 6 (RFX6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Regulatory Factor X 6 (RFX6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Regulatory Factor X 6 (RFX6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Regulatory Factor X 6 (RFX6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Regulatory Factor X 6 (RFX6) ELISA Kit Customized Service Offer
  1. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Identification and characterization of novel human tissue-specific RFX transcription factors."BMC Evol. Biol. 8:226-226(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Rfx6 directs islet formation and insulin production in mice and humans." Nature 463:775-780(2010) [PubMed] [Europe PMC] [Abstract]