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Retinol Dehydrogenase 10 (RDH10)

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SDR16C4; Short Chain Dehydrogenase/Reductase Family 16C,Member 4

Retinol Dehydrogenase 10 (RDH10)
CCC H240
HGNC 19975
MGI 1924238
PubMed 19458327
RGD 727793
UniProt Q8IZV5
RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR) when the retinal pigment epithelium (RPE) is illuminated.
The deduced 341-amino acid RDH10 protein has a calculated molecular mass of about 38 kD. It shares significant sequence homology with other SDRs, and it shares 100% and 98.6% amino acid identity with the bovine and murine Rdh10 proteins, respectively. Northern blot analysis of bovine tissues detected a 3-kb transcript only in RPE. Real-time PCR revealed high expression in RPE and low expression in most other tissues tested.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 10 (RDH10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 10 (RDH10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 10 (RDH10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 10 (RDH10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 10 (RDH10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 10 (RDH10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Retinol Dehydrogenase 10 (RDH10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Retinol Dehydrogenase 10 (RDH10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Retinol Dehydrogenase 10 (RDH10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Retinol Dehydrogenase 10 (RDH10) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE."Invest. Ophthalmol. Vis. Sci. 43:3365-3372(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Genomic organization and transcription of the human retinol dehydrogenase 10 (RDH10) gene."FEBS Lett. 554:59-66(2003) [PubMed] [Europe PMC] [Abstract]