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RalA Binding Protein 1 (RALBP1)

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RIP; RIP1; RLIP76; 76 kDa Ral-interacting protein; Ral-interacting protein 1; Dinitrophenyl S-glutathione ATPase

RalA Binding Protein 1 (RALBP1)
CCC H265
HGNC 9841
MGI 108466
PubMed 21822277
RGD 621134
UniProt Q15311
Wiki RALBP1
Small G proteins have GDP-bound inactive and GTP-bound active forms; RAL proteins shift from the inactive to the active state through the actions of RALGDS. RALGDS interacts with the active form of RAS.
The deduced 655-amino acid protein is homologous in the central region to proteins bearing a CDC42 /RHO /RAC GTPase-activating protein (GAP) activity, such as BCR. Sequence analysis predicted that RALBP1 has an N-terminal alpha-helical region, the GAP-like region, the RAL-binding region, and the C-terminal region. Binding analysis showed that RALBP1 interacts with RALA and RALB but with no other GTPase except RAC1. Northern blot analysis detected ubiquitous, low-level expression of RALBP1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH265Hu01 Recombinant RalA Binding Protein 1 (RALBP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPH265Hu02 Recombinant RalA Binding Protein 1 (RALBP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH265Hu01 Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC; IP.
PAH265Hu02 Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC; IP.
LAH265Hu71 Biotin-Linked Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC.
Assay Kits SEH265Hu ELISA Kit for RalA Binding Protein 1 (RALBP1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH265Mu01 Recombinant RalA Binding Protein 1 (RALBP1) Positive Control; Immunogen; SDS-PAGE; WB.
RPH265Mu02 Recombinant RalA Binding Protein 1 (RALBP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH265Mu01 Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC; IP.
PAH265Mu02 Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC; IP.
LAH265Mu71 Biotin-Linked Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for RalA Binding Protein 1 (RALBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RalA Binding Protein 1 (RALBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH265Ra01 Recombinant RalA Binding Protein 1 (RALBP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH265Ra01 Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC; IP.
LAH265Ra71 Biotin-Linked Polyclonal Antibody to RalA Binding Protein 1 (RALBP1) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for RalA Binding Protein 1 (RALBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RalA Binding Protein 1 (RALBP1) ELISA Kit Customized Service Offer
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  17. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  18. "The RalB-RLIP76 complex reveals a novel mode of ral-effector interaction."Structure 18:985-995(2010) [PubMed] [Europe PMC] [Abstract]