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Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6)

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CGM3; PSG10; PSG12; PSGGB; Pregnancy-specific glycoprotein 10

Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6)
CCC H296
HGNC 9523
PubMed 11327547
UniProt Q00889
Wiki PSG6
The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily.
PSG10, which had been thought to be a novel gene, is in fact an allelic variant of PSG6 that differs by 10 bp in the coding region.The PSG genes are tandemly oriented in a 5-prime to 3-prime direction from telomere to centromere. The CEA subgroup gene CGM11 is located at the telomeric end of the PSG gene cluster, and 6 genes belonging to a third CEA family subgroup, namely CGM13 through CGM18 (later found to be pseudogenes), are interspersed among the PSG genes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Pregnancy Specific Beta-1-Glycoprotein 6 (PSG6) ELISA Kit Customized Service Offer
  1. "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver."Biochem. Biophys. Res. Commun. 163:1197-1209(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of cDNAs of the human pregnancy-specific beta-1-glycoprotein family, a new subfamily of the immunoglobulin gene superfamily."Biochemistry 29:2845-2852(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Characterization of two new members of the pregnancy-specific beta 1-glycoprotein family from the myeloid cell line KG-1 and suggestion of two distinct classes of transcription unit."Biochemistry 29:10213-10218(1990) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed."Biochem. Biophys. Res. Commun. 167:848-859(1990) [PubMed] [Europe PMC] [Abstract]
  7. "Evolution of the carcinoembryonic antigen family. structures of CGM9, CGM11 and pregnancy-specific glycoprotein promoters."Tumor Biol. 21:63-81(2000) [PubMed] [Europe PMC] [Abstract]
  8. "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons."Biochem. Biophys. Res. Commun. 158:996-1004(1989) [PubMed] [Europe PMC] [Abstract]
  9. "Linkage of two human pregnancy-specific beta 1-glycoprotein genes: one is associated with hydatidiform mole."Proc. Natl. Acad. Sci. U.S.A. 87:5822-5826(1990) [PubMed] [Europe PMC] [Abstract]