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Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)

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LEM6; PGC-1(alpha); PGC-1v; PGC1; PGC1A; PPARGC1; Ligand effect modulator 6

Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)
CCC H337
HGNC 9237
MGI 1342774
PubMed 23335958
RGD 620925
UniProt Q9UBK2
Wiki PPARGC1A
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with the nuclear receptor PPAR-γ, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH337Hu01 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPH337Hu02 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH337Hu01 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
MAH337Hu21 Monoclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
PAH337Hu02 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
Assay Kits SEH337Hu ELISA Kit for Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH337Mu01 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPH337Mu02 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH337Mu01 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
PAH337Mu02 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
Assay Kits SEH337Mu ELISA Kit for Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH337Ra01 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
RPH337Ra02 Recombinant Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH337Ra01 Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
MAH337Ra21 Monoclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) WB; IHC; ICC; IP.
Assay Kits SEH337Ra ELISA Kit for Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Enzyme-linked immunosorbent assay for Antigen Detection.
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  12. "Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells."J. Biol. Chem. 288:25207-25218(2013) [PubMed] [Europe PMC] [Abstract]