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Peptidase, Mitochondrial Processing Alpha (PMPCa)

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Alpha-MPP; INPP5E; Inositol Polyphosphate-5-Phosphatase,72 kD

Peptidase, Mitochondrial Processing Alpha (PMPCa)
CCC H348
HGNC 18667
MGI 1918568
PubMed 7836378
RGD 727897
UniProt Q10713
Wiki PMPCA
By sequencing clones obtained from a size-fractionated KG-1 myeloid leukemia cell line cDNA library, Nagase et al. (1995) cloned PMPCA, which they designated KIAA0123. The deduced 528-amino acid protein contains an insulinase (IDE) motif and shares 85.5% identity with the rat mitochondrial processing protease. Northern blot analysis detected PMPCA expression in all tissues and cell lines examined, with highest expression in HeLa cells, heart, skeletal muscle, and testis.
Hartz (2009) mapped the PMPCA gene to chromosome 9q34.3 based on an alignment of the PMPCA sequence with the genomic sequence (GRCh37). The PMPCA gene overlaps the INPP5E gene and is transcribed in the opposite direction.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidase, Mitochondrial Processing Alpha (PMPCa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidase, Mitochondrial Processing Alpha (PMPCa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Peptidase, Mitochondrial Processing Alpha (PMPCa) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Peptidase, Mitochondrial Processing Alpha (PMPCa) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) CLIA Kit Customized Service Offer
n/a ELISA Kit for Peptidase, Mitochondrial Processing Alpha (PMPCa) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 2:37-43(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 2:167-174(1995) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Cluster analysis of an extensive human breast cancer cell line protein expression map database."Proteomics 2:212-223(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]