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Plexin B2 (PLXNB2)

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PLEXB2; MM1

Plexin B2 (PLXNB2)
CCC H359
HGNC 9104
MGI 2154239
PubMed 21966369
RGD 1305495
UniProt O15031
Wiki PLXNB2
Members of the B class of plexins, such as PLXNB2 is related to human SEP (PLXNB1). RT-PCR detected highest PLXNB2 expression in testis and ovary, followed by placenta, lung, liver, and kidney. Much lower expression was detected in prostate and small intestine, and little to none was detected in other tissues examined.
Ligand-induced dimerization of plexin B was sufficient to stimulate endogenous RhoA (ARHA) potently and induce the reorganization of the cytoskeleton in mammalian cells. Overexpression of the PDZ domain of PDZ-RhoGEF prevented cell rounding and neurite retraction in differentiated rat neural precursor cells induced by activation of endogenous PLXNB1 by semaphorin-4D .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plexin B2 (PLXNB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plexin B2 (PLXNB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plexin B2 (PLXNB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plexin B2 (PLXNB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plexin B2 (PLXNB2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plexin B2 (PLXNB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plexin B2 (PLXNB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plexin B2 (PLXNB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plexin B2 (PLXNB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plexin B2 (PLXNB2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plexin B2 (PLXNB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plexin B2 (PLXNB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plexin B2 (PLXNB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plexin B2 (PLXNB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plexin B2 (PLXNB2) ELISA Kit Customized Service Offer
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  4. "Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF."J. Biol. Chem. 277:43115-43120(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Functional regulation of semaphorin receptors by proprotein convertases."J. Biol. Chem. 278:10094-10101(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Interplay between scatter factor receptors and B plexins controls invasive growth."Oncogene 23:5131-5137(2004) [PubMed] [Europe PMC] [Abstract]
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  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]