Tamagnone et al. (1999) identified the cDNA sequence of a novel member of the plexin gene family, which they called plexin B3.Artigiani et al. (2004) showed that mammalian Plxnb3 is a high-affinity semaphorin-5A (SEMA5A) receptor. Plxnb3 was activated by Sema5a, and the Sema5a-Plxnb3 complex triggered intracellular signaling through Met, the receptor for hepatocyte growth factor.Tamagnone et al. (1999) found the PLXNB3 coding sequence in the genomic sequence of the ABCD1 gene on Xq28.Matsumoto et al. (2005) identified a partial deletion (exons 3 to 10) of the ABCD1 gene with fusion to the neighboring PLXNB3 gene. Sequencing showed that the breakpoints were at nucleotide +1374 in intron 2 of the ABCD1 gene and nucleotide +915 in intron 2 of the PLXNB3 gene.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Plexin B3 (PLXNB3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Plexin B3 (PLXNB3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Plexin B3 (PLXNB3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Plexin B3 (PLXNB3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Plexin B3 (PLXNB3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Plexin B3 (PLXNB3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Plexin B3 (PLXNB3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Plexin B3 (PLXNB3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Plexin B3 (PLXNB3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Plexin B3 (PLXNB3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Plexin B3 (PLXNB3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Plexin B3 (PLXNB3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Plexin B3 (PLXNB3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Plexin B3 (PLXNB3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Plexin B3 (PLXNB3) | ELISA Kit Customized Service Offer |
- "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "Interplay between scatter factor receptors and B plexins controls invasive growth."Oncogene 23:5131-5137(2004) [PubMed] [Europe PMC] [Abstract]
- "Plexin-B3 is a functional receptor for semaphorin 5A."EMBO Rep. 5:710-714(2004) [PubMed] [Europe PMC] [Abstract]
- "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin."BMC Neurosci. 6:53-53(2005) [PubMed] [Europe PMC] [Abstract]
- "Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase."J. Biol. Chem. 285:32436-32445(2010) [PubMed] [Europe PMC] [Abstract]
- "Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton."Oncogene 31:595-610(2012) [PubMed] [Europe PMC] [Abstract]