Pipecolic Acid Oxidase (PIPOX)
[Edit]LPIPOX; PSO; L-Pipecolic Acid Oxidase; L-pipecolate oxidase; Peroxisomal sarcosine oxidase
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L-Pipecolic acid oxidase activity is deficient in patients with peroxisome biogenesis disorders (PBDs). The cDNA was cloned with the use of a reverse genetics approach based on the amino acid sequence obtained from purified L-pipecolic acid oxidase from monkey.
The complete cDNA, obtained by conventional library screening and 5' rapid amplification of cDNA ends, encompassed an open reading frame of 1170 bases, translating to a 390-residue protein. The recombinant enzyme oxidized both L-pipecolic acid and sarcosine. However, PBD patients who lack the enzyme activity accumulate only L-pipecolic acid, suggesting that in humans in vivo, this enzyme is involved mainly in the degradation of L-pipecolic acid.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Pipecolic Acid Oxidase (PIPOX) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Pipecolic Acid Oxidase (PIPOX) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Pipecolic Acid Oxidase (PIPOX) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Pipecolic Acid Oxidase (PIPOX) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Pipecolic Acid Oxidase (PIPOX) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Pipecolic Acid Oxidase (PIPOX) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Pipecolic Acid Oxidase (PIPOX) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Pipecolic Acid Oxidase (PIPOX) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Pipecolic Acid Oxidase (PIPOX) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Pipecolic Acid Oxidase (PIPOX) | ELISA Kit Customized Service Offer |
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- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]