-97428.jpg)
Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product .
The deduced 505-amino acid protein contains a predicted signal sequence, several transmembrane regions, and potential N-glycosylation sites. Northern blot analysis detected a 6-kb transcript in heart, kidney, liver, colon, placenta, skeletal muscle, and pancreas, with low expression in brain and no expression in spleen. The 3-prime untranslated region contains several SINEs, including Alu and MIR sequences. The predicted protein has 506 amino acids. RT-PCR ELISA detected high to moderate expression in all adult and fetal human tissues and all specific brain regions tested.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH428Hu01 | Recombinant Prenylcysteine Oxidase 1 (PCYOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAH428Hu01 | Polyclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | WB,IHC |
| MAH428Hu21 | Monoclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEH428Hu | ELISA Kit for Prenylcysteine Oxidase 1 (PCYOX1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPH428Mu01 | Recombinant Prenylcysteine Oxidase 1 (PCYOX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPH428Mu02 | Recombinant Prenylcysteine Oxidase 1 (PCYOX1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAH428Mu01 | Polyclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | WB; IHC; ICC; IP. |
| PAH428Mu02 | Polyclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | WB; IHC; ICC; IP. | |
| Assay Kits | SEH428Mu | ELISA Kit for Prenylcysteine Oxidase 1 (PCYOX1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Prenylcysteine Oxidase 1 (PCYOX1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Prenylcysteine Oxidase 1 (PCYOX1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Prenylcysteine Oxidase 1 (PCYOX1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Prenylcysteine Oxidase 1 (PCYOX1) | ELISA Kit Customized Service Offer |
- "Cloning, expression, and cellular localization of a human prenylcysteine lyase."J. Biol. Chem. 274:35802-35808(1999) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]