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Nuclear Receptor Binding Factor 2 (NRBF2)

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COPR1; COPR2; NRBF-2; Comodulator of PPAR and RXR

Nuclear Receptor Binding Factor 2 (NRBF2)
CCC H521
HGNC 19692
MGI 1354950
PubMed 10786636
RGD 61937
UniProt Q96F24
Wiki NRBF2
A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor alpha as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast.
NRBF2 was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha. NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR. NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression. Alternative names for NRBF2 include COPR1, COPR2, and NRBF-2.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Binding Factor 2 (NRBF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Binding Factor 2 (NRBF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Binding Factor 2 (NRBF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Binding Factor 2 (NRBF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Binding Factor 2 (NRBF2) ELISA Kit Customized Service Offer
  1. "Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator."J. Invest. Dermatol. 123:1092-1101(2004) [PubMed] [Europe PMC] [Abstract]
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  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
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  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  10. "Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC."EMBO J. 31:1931-1946(2012) [PubMed] [Europe PMC] [Abstract]