Neuronal PAS Domain Protein 1 (NPAS1)
[Edit]MOP5; PASD5; bHLHe11; Neuronal PAS1; Basic-helix-loop-helix-PAS protein MOP5; Class E basic helix-loop-helix protein 11; PAS domain-containing protein 5
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NPAS1 is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development.
The predicted 590-amino acid human NPAS1 protein shares 86% sequence identity with mouse Npas1. Northern blot analysis of mouse tissues revealed that Npas1 is expressed predominantly in brain. In situ hybridization indicated that the pattern of Npas1 mRNA distribution in mouse brain is broad and complex, and is largely nonoverlapping with that of Npas2.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neuronal PAS Domain Protein 1 (NPAS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neuronal PAS Domain Protein 1 (NPAS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Neuronal PAS Domain Protein 1 (NPAS1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Neuronal PAS Domain Protein 1 (NPAS1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Neuronal PAS Domain Protein 1 (NPAS1) | ELISA Kit Customized Service Offer |
- "Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system."Proc. Natl. Acad. Sci. U.S.A. 94:713-718(1997) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway."J. Biol. Chem. 272:8581-8593(1997) [PubMed] [Europe PMC] [Abstract]