≡

Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4)

[Edit]

NAP2; NAP2L; hNAP2; Nucleosome assembly protein 2

Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4)
CCC H570
HGNC 7640
MGI 1316687
PubMed 8923002
RGD 1305391
UniProt Q99733
Wiki NAP1L4
NAP1L4 encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.This gene is homologous to the yeast nucleosome assembly protein NAP1. The authors designated the new gene NAP2. The NAP2 gene encodes a highly acidic protein of 375 amino acids. A 1,200-bp 3-prime untranslated region was present.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Polyclonal Antibody Customized Service Offer
Assay Kits SEH570Ra ELISA Kit for Nucleosome Assembly Protein 1 Like Protein 4 (NAP1L4) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues."Hum. Mol. Genet. 5:1743-1748(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."J. Proteome Res. 6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]