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Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2)

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Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2)
CCC H669
HGNC 6984
MGI 2147351
PubMed 1993674
RGD 1310321
UniProt P23368
Wiki ME2
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene.
Alternatively spliced transcript variants encoding different isoforms found for this gene.The deduced 584-amino acid precursor protein has a calculated molecular mass of 65.4 kD. The 5-prime untranslated region of the transcript contains an 80-nucleotide sequence that is extremely G/C rich (76.3%). ME2 contains a mitochondrial leader sequence, an amphiphilic alpha helix, an ADP-binding fold, and a putative dinucleotide-binding domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH669Hu01 Recombinant Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Positive Control; Immunogen; SDS-PAGE; WB.
APH669Hu01 Active Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Cell culture; Activity Assays.
Antibodies PAH669Hu01 Polyclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) WB; IHC
MAH669Hu21 Monoclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) WB; IHC; ICC; IP.
Assay Kits SEH669Hu ELISA Kit for Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Malic Enzyme 2, NADP+ Dependent, Mitochondrial (ME2) ELISA Kit Customized Service Offer
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