≡

Microtubule Associated Serine/Threonine Kinase 2 (MAST2)

[Edit]

MAST205; MTSSK

Microtubule Associated Serine/Threonine Kinase 2 (MAST2)
CCC H682
HGNC 19035
MGI 894676
PubMed 15308666
RGD 1304573
UniProt Q6P0Q8
Wiki MAST2
The deduced 1,265-amino acid protein shares significant similarity with mouse Mast205. RT-PCR ELISA detected variable MAST2 expression in all tissues examined. The deduced 1,734-amino acid protein has a calculated molecular mass of 190.5 kD. It had an apparent molecular mass of 205 kD by SDS-PAGE. Mast205 contains a central serine/threonine kinase catalytic domain, which includes an ATP-binding consensus sequence, and several potential phosphorylation sites. Northern blot analysis of mouse tissues detected Mast205 expression only in testis. Mast205 expression increased during postnatal testicular development coincident with meiosis/spermiogenesis. Immunofluorescence microscopy showed Mast205 associated with mouse spermatid manchette.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH682Hu01 Recombinant Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH682Hu01 Polyclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) WB; IHC; ICC; IP.
MAH682Hu21 Monoclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) WB; IHC; ICC; IP.
Assay Kits SEH682Hu ELISA Kit for Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Microtubule Associated Serine/Threonine Kinase 2 (MAST2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microtubule Associated Serine/Threonine Kinase 2 (MAST2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Microtubule Associated Serine/Threonine Kinase 2 (MAST2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Microtubule Associated Serine/Threonine Kinase 2 (MAST2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microtubule Associated Serine/Threonine Kinase 2 (MAST2) ELISA Kit Customized Service Offer
  1. "Protocadherin LKC, a new candidate for a tumor suppressor of colon and liver cancers, its association with contact inhibition of cell proliferation."Carcinogenesis 23:1139-1148(2002) [PubMed] [Europe PMC] [Abstract].
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] and Placenta.
  4. "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:277-286(1998) [PubMed] [Europe PMC] [Abstract].
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Increased activity associated with the MAST205 protein kinase complex during mammalian spermiogenesis."Biol. Reprod. 55:1039-1044(1996) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]