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Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3)

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LPNA3; Liprin-Alpha 3; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3

Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3)
CCC H740
HGNC 9247
MGI 1924037
PubMed 14612982
UniProt O75145
PPFIA3 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. Liprin family protein has been shown to localize phosphatase LAR to cell focal adhesions and may be involved in the molecular organization of presynaptic active zones.
Since the first ATG was not within a Kozak consensus region, the KIAA0654 cDNA may lack some 5-prime sequences.The predicted 1,093-amino acid polypeptide shares 52% sequence identity with LIP1. The in vitro transcribed/translated product of the cDNA had a molecular mass of greater than 100 kD by SDS-PAGE. RT-PCR revealed that liprin-alpha-3 is expressed in several tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase F Interacting Protein 3 (PPFIA3) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins."J. Biol. Chem. 273:15611-15620(1998) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]