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V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)

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C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS3; RASK2

V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS)
CCC H751
HGNC 6407
MGI 96680
PubMed 6308466
RGD 2981
UniProt P01116
Wiki KRAS
Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. When mutated, KRAS is a oncogene. The protein product of the normal KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.KRAS acts as a molecular on/off switch, once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. KRAS binds to GTP in the active state and possesses an intrinsic enzymatic activity which cleaves the terminal phosphate of the nucleotide converting it to GDP.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH751Hu01 Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAH751Hu21 Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) WB; IHC; ICC; IP.
PAH751Hu01 Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) WB; IHC; ICC; IP.
Assay Kits SEH751Hu ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Polyclonal Antibody Customized Service Offer
Assay Kits SEH751Mu ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) CLIA Kit Customized Service Offer
n/a ELISA Kit for V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) ELISA Kit Customized Service Offer
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