Influenza Virus NS1A Binding Protein (IVNS1ABP)

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ND1; NS-1; NS1-BP; NS1BP; ARA3; FLARA3; Aryl hydrocarbon receptor-associated protein 3

Influenza Virus NS1A Binding Protein (IVNS1ABP)
The deduced 619-amino acid protein has a calculated molecular mass of 69.7 kD. NS1BP contains an N-terminal BTB/POZ domain that covers about 120 amino acids, followed by 5 imperfect tandem kelch repeats of 47 to 49 amino acids. Northern blot analysis of HeLa cell mRNA detected an NS1BP transcript of about 3.1 kb. Western blot analysis detected endogenous NS1BP as a protein doublet of about 70 kD in 3 human epithelium-derived cell lines. Immunofluorescence analysis of HeLa cells revealed a punctate nuclear staining pattern that colocalized with the spliceosome assembly factor SC35 (SFRS2) and excluded nucleoli.highest levels in kidney and ovary, followed by brain, liver, testis, heart, lung, and pancreas. Intermediate expression was detected in skeletal muscle and spleen.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Influenza Virus NS1A Binding Protein (IVNS1ABP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Influenza Virus NS1A Binding Protein (IVNS1ABP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Influenza Virus NS1A Binding Protein (IVNS1ABP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Influenza Virus NS1A Binding Protein (IVNS1ABP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Influenza Virus NS1A Binding Protein (IVNS1ABP) ELISA Kit Customized Service Offer
  1. "NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells."J. Virol. 72:7170-7180(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein."Mol. Pharmacol. 70:8-15(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  9. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  11. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  12. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  15. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]