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Interferon Regulatory Factor 9 (IRF9)

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ISGF3G; ISGF3; p48; Interferon-Stimulated Transcription Factor 3,Gamma 48kDa; IFN-alpha-responsive transcription factor subunit; Interferon-stimulated gene factor 3 gamma

Interferon Regulatory Factor 9 (IRF9)
CCC H780
HGNC 6131
MGI 107587
PubMed 22902549
RGD 1308766
UniProt Q00978
Wiki IRF9
ISGF3 is an interferon-dependent, positive-acting transcription factor that is cytoplasmically activated, possibly through direct interaction with the interferon receptor.
The attachment of interferon-alpha (IFNA) to a specific cell surface receptor activates the transcription of a limited set of genes termed the IFN-stimulated genes. Supporting the notion that the proteins in ISGF3 are links between an occupied receptor and a limited set of genes were the observations that the proteins preexist in untreated cells, are promptly activated in an IFN-alpha-dependent fashion in the cell cytoplasm, and are subsequently translocated to the nucleus. Four proteins of 48 (ISGF3G), 84, 91, and 113 kD (STAT2) make up the ISGF3 complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH780Hu01 Recombinant Interferon Regulatory Factor 9 (IRF9) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH780Hu01 Polyclonal Antibody to Interferon Regulatory Factor 9 (IRF9) WB; IHC; ICC; IP.
MAH780Hu21 Monoclonal Antibody to Interferon Regulatory Factor 9 (IRF9) WB; IHC; ICC; IP.
Assay Kits SEH780Hu ELISA Kit for Interferon Regulatory Factor 9 (IRF9) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Regulatory Factor 9 (IRF9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Regulatory Factor 9 (IRF9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Regulatory Factor 9 (IRF9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Regulatory Factor 9 (IRF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Regulatory Factor 9 (IRF9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interferon Regulatory Factor 9 (IRF9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interferon Regulatory Factor 9 (IRF9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interferon Regulatory Factor 9 (IRF9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interferon Regulatory Factor 9 (IRF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interferon Regulatory Factor 9 (IRF9) ELISA Kit Customized Service Offer
  1. "Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins."Mol. Cell. Biol. 12:3315-3324(1992) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation."J. Interferon Cytokine Res. 22:103-109(2002) [PubMed] [Europe PMC] [Abstract]
  4. "Viral inhibition of interferon signal transduction."Intervirology 42:325-330(1999) [PubMed] [Europe PMC] [Abstract]