Interleukin 1 Receptor Like Protein 1 (IL1RL1)
[Edit]T1; IL33R; ST2; DER4; FIT-1; ST2L; ST2V; Homolog Of Mouse Growth Stimulation-Expressed
IL1RL1 is a member of the interleukin-1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. IL1RL1 encodes a protein of 556 amino acids (molecular weight 63,358 Da). Both membrane bound and soluble forms are known. The protein is known to interact with MyD88, IRAK1, IRAK4 and TRAF6. It appears to be essential for the normal function of T helper cells type 2 (Th2 cells).
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPH820Hu01 | Recombinant Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPH820Hu02 | Recombinant Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPH820Hu03 | Recombinant Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAH820Hu01 | Polyclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | WB; IHC |
PAH820Hu02 | Polyclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | WB; IHC; ICC; IP. | |
LAH820Hu71 | Biotin-Linked Polyclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | WB; IHC; ICC. | |
Assay Kits | SEH820Hu | ELISA Kit for Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Interleukin 1 Receptor Like Protein 1 (IL1RL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Interleukin 1 Receptor Like Protein 1 (IL1RL1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Interleukin 1 Receptor Like Protein 1 (IL1RL1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Interleukin 1 Receptor Like Protein 1 (IL1RL1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Interleukin 1 Receptor Like Protein 1 (IL1RL1) | ELISA Kit Customized Service Offer |
- "Nucleotide sequence of a complementary DNA for human ST2."Biochim. Biophys. Acta 1171:215-218(1992) [PubMed] [Europe PMC] [Abstract]
- "Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM."Biochem. Biophys. Res. Commun. 264:14-18(1999) [PubMed] [Europe PMC] [Abstract]
- "The cloning and nucleotide sequence of human ST2L cDNA."Genomics 67:284-290(2000) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
- "Tissue distribution and subcellular localization of a variant form of the human ST2 gene product, ST2V."Biochem. Biophys. Res. Commun. 285:1377-1383(2001) [PubMed] [Europe PMC] [Abstract]
- "IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST 2 and induces T helper type 2-associated cytokines."Immunity 23:479-490(2005) [PubMed] [Europe PMC] [Abstract]
- "An unappreciated role for RNA surveillance."Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
- "Structural insights into the interaction of IL-33 with its receptors."Proc. Natl. Acad. Sci. U.S.A. 110:14918-14923(2013) [PubMed] [Europe PMC] [Abstract]