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Isocitrate Dehydrogenase 3 Beta (IDH3b)

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H-IDHB; Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Isocitric dehydrogenase subunit beta; NAD(+)-specific ICDH subunit beta

Isocitrate Dehydrogenase 3 Beta (IDH3b)
CCC H836
HGNC 5385
MGI 2158650
PubMed 22387199
RGD 621881
UniProt O43837
Wiki IDH3B
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.
IDH3b is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Isocitrate Dehydrogenase 3 Beta (IDH3b) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) CLIA Kit Customized Service Offer
n/a ELISA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Isocitrate Dehydrogenase 3 Beta (IDH3b) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) CLIA Kit Customized Service Offer
n/a ELISA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Isocitrate Dehydrogenase 3 Beta (IDH3b) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Isocitrate Dehydrogenase 3 Beta (IDH3b) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) CLIA Kit Customized Service Offer
n/a ELISA Kit for Isocitrate Dehydrogenase 3 Beta (IDH3b) ELISA Kit Customized Service Offer
  1. "Identification and functional characterization of a novel, tissue-specific NAD+-dependent isocitrate dehydrogenase beta subunit isoform."J. Biol. Chem. 274:36866-36875(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle."Nat. Genet. 40:1230-1234(2008) [PubMed] [Europe PMC] [Abstract]