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Hornerin (HRNR)

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S100a18

Hornerin (HRNR)
CCC H884
HGNC 20846
MGI 1915973
PubMed 17051244
UniProt Q86YZ3
Hornerin was expressed in the upper epidermis of newborn mouse skin, as was profilaggrin. In addition, both hornerin and profilaggrin were expressed in the tongue, esophagus, and forestomach. In all four tissues, immunostaining for hornerin and profilaggrin showed a granular pattern, and most of the signals for the two proteins were co-localized on keratohyalin granules. This was confirmed by double immunoelectron microscopy. Within keratohyalin granules, hornerin was detected more frequently in the periphery, whereas profilaggrin was equally distributed. A quantitative RT-PCR revealed that both genes were expressed at highest levels in the forestomach and at the next highest levels in skin. Profilaggrin mRNA was most abundant in the forestomach. In skin, the amount of hornerin mRNA was more than fourfold greater than the amount of profilaggrin mRNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH884Hu01 Recombinant Hornerin (HRNR) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH884Hu01 Polyclonal Antibody to Hornerin (HRNR) WB; IHC; ICC; IP.
MAH884Hu21 Monoclonal Antibody to Hornerin (HRNR) WB; IHC; ICC; IP.
Assay Kits SEH884Hu ELISA Kit for Hornerin (HRNR) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hornerin (HRNR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hornerin (HRNR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hornerin (HRNR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hornerin (HRNR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hornerin (HRNR) ELISA Kit Customized Service Offer
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  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Hornerin is a component of the epidermal cornified cell envelopes."FASEB J. 25:1567-1576(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Ultraviolet B irradiation induces the expression of hornerin in xenotransplanted human skin."Acta Histochem. 116:20-24(2014) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]