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Homeobox Protein B2 (HOXB2)

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HOX2; HOX2H; Hox-2.8; K8

Homeobox Protein B2 (HOXB2)
CCC H892
HGNC 5113
MGI 96183
PubMed 23197710
RGD 1309853
UniProt P14652
Wiki HOXB2
HOXB2 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.
In human and mouse tissues, expression of HOXB2 persisted in adult spinal cord and was primarily localized in nuclei of motor neurons. In G93A transgenic mice, HOXB2 colocalized with mutant SOD1 and was redistributed to perikarya and proximal neurites of motor neurons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein B2 (HOXB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein B2 (HOXB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein B2 (HOXB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein B2 (HOXB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein B2 (HOXB2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein B2 (HOXB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein B2 (HOXB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein B2 (HOXB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein B2 (HOXB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein B2 (HOXB2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Homeobox Protein B2 (HOXB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Homeobox Protein B2 (HOXB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Homeobox Protein B2 (HOXB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Homeobox Protein B2 (HOXB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Homeobox Protein B2 (HOXB2) ELISA Kit Customized Service Offer
  1. "The human HOX gene family."Nucleic Acids Res. 17:10385-10402(1989) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Differential expression of human HOX-2 genes along the anterior-posterior axis in embryonic central nervous system."Differentiation 40:191-197(1989) [PubMed] [Europe PMC] [Abstract]
  4. "Organization of human class I homeobox genes."Genome 31:745-756(1989) [PubMed] [Europe PMC] [Abstract]
  5. "Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages."EMBO J. 7:2131-2138(1988) [PubMed] [Europe PMC] [Abstract]
  6. "Transcription factor GATA-1 regulates human HOXB2 gene expression in erythroid cells."J. Biol. Chem. 270:4544-4550(1995) [PubMed] [Europe PMC] [Abstract]
  7. "The gammaPE complex contains both SATB1 and HOXB2 and has positive and negative roles in human gamma-globin gene regulation."DNA Cell Biol. 18:805-817(1999) [PubMed] [Europe PMC] [Abstract]