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Heme Binding Protein 1 (HEBP1)

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HEBP; HBP; p22HBP

Heme Binding Protein 1 (HEBP1)
CCC H920
HGNC 17176
MGI 1333880
PubMed 21709160
RGD 1304581
UniProt Q9NRV9
F2L is an acetylated 21-amino acid peptide derived from the N terminus of intracellular HBP. F2L bound and activated FPRL2 in the nanomolar range, triggering intracellular calcium release, inhibition of cAMP accumulation, and phosphorylation of MAP kinases. Testing on monocytes and monocyte-derived dendritic cells showed that F2L promoted calcium mobilization and chemotaxis.
Sequence analysis predicted that the 189-amino acid human HBP protein, which is 80% identical to the mouse sequence, contains a conserved hydrophobic heme-binding region not found in SOUL. Northern blot analysis detected a 1.5-kb Hbp transcript in mouse liver.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heme Binding Protein 1 (HEBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heme Binding Protein 1 (HEBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heme Binding Protein 1 (HEBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heme Binding Protein 1 (HEBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heme Binding Protein 1 (HEBP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heme Binding Protein 1 (HEBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heme Binding Protein 1 (HEBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heme Binding Protein 1 (HEBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heme Binding Protein 1 (HEBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heme Binding Protein 1 (HEBP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Heme Binding Protein 1 (HEBP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Heme Binding Protein 1 (HEBP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Heme Binding Protein 1 (HEBP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Heme Binding Protein 1 (HEBP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heme Binding Protein 1 (HEBP1) ELISA Kit Customized Service Offer
  1. "Discovery of a putative heme-binding protein family (SOUL/HBP) by two-tissue suppression subtractive hybridization and database searches."Brain Res. Mol. Brain Res. 74:175-181(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of a human and mouse tetrapyrrole-binding protein."Arch. Biochem. Biophys. 407:196-201(2002) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]