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Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1)

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GRF-1; P190-A; P190A; p190RhoGAP; Glucocorticoid receptor repression factor 1; Rho GAP p190A

Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1)
CCC H961
HGNC 4591
MGI 1929494
PubMed 12234678
RGD 1308738
UniProt Q9NRY4
Wiki GRLF1
The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines.
The GRLF1 enhances the homologous down-regulation of wild-type hGR gene expression. Biochemical analysis suggests that GRLF1 interaction is sequence specific and that transcriptional efficacy of GRLF1 is regulated through its interaction with specific sequence motif. The level of expression is regulated by glucocorticoids.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glucocorticoid Receptor DNA Binding Factor 1 (GRLF1) ELISA Kit Customized Service Offer
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