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Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM)

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GPAT1

Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM)
CCC H983
HGNC 24865
MGI 109162
PubMed 22070544
RGD 61847
UniProt Q9HCL2
Wiki GPAM
Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynthesis, is predicted to play a pivotal role in the regulation of cellular triacylglycerol and phospholipid levels. Two mammalian forms of GPAT have been identified on the basis of localization to either the endoplasmic reticulum or mitochondria.
Mitochondrial Gpat, or Gpam, is highly expressed in mouse lipogenic tissues, such as liver and adipose tissue. In animal studies, fasting/refeeding and administration of insulin caused a dramatic induction of Gpat. Consistent with these observations, putative carbohydrate-responsive sequences were identified in the proximal promoter of the murine cDNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH983Hu01 Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH983Hu01 Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) WB; IHC; ICC; IP.
MAH983Hu21 Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) WB; IHC; ICC; IP.
Assay Kits SEH983Hu ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) CLIA Kit Customized Service Offer
n/a ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH983Ra01 Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAH983Ra01 Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) WB; IHC; ICC; IP.
MAH983Ra21 Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) WB; IHC; ICC; IP.
Assay Kits SEH983Ra ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase."J. Biol. Chem. 283:10048-10057(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]