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Golgi SNAP Receptor Complex Member 1 (GOSR1)

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P28; GOS28; GOS28/P28; GS28; GOLIM2; Golgi Integral Membrane Protein 2; 28 kDa Golgi SNARE protein; 28 kDa cis-Golgi SNARE p28

Golgi SNAP Receptor Complex Member 1 (GOSR1)
CCC H986
HGNC 4430
MGI 1858260
PubMed 11927603
RGD 71093
UniProt O95249
Wiki GOSR1
GOSR1 encodes a trafficking membrane protein which transports proteins among the endoplasmic reticulum and the Golgi and between Golgi compartments. This protein is considered an essential component of the Golgi SNAP receptor (SNARE) complex. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Sequence analysis revealed that the predicted protein contained a central coiled-coil domain and a C-terminal membrane anchor. The authors found that GS28 is a core component of the Golgi 20S SNARE complex that participates in the docking or fusion stage of endoplasmic reticulum-Golgi transport.The deduced 250-amino acid human protein is 97% identical to rat GS28.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgi SNAP Receptor Complex Member 1 (GOSR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgi SNAP Receptor Complex Member 1 (GOSR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgi SNAP Receptor Complex Member 1 (GOSR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgi SNAP Receptor Complex Member 1 (GOSR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgi SNAP Receptor Complex Member 1 (GOSR1) ELISA Kit Customized Service Offer
  1. "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning."Proc. Natl. Acad. Sci. U.S.A. 95:8175-8180(1998) [PubMed] [Europe PMC] [Abstract]
  2. "cDNA characterization and chromosomal mapping of human Golgi SNARE GS27 and GS28 to chromosome 17."Genomics 57:285-288(1999) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network."Mol. Biol. Cell 15:4011-4022(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells."J. Cell Biol. 168:747-759(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Low-temperature-induced Golgi tubules are transient membranes enriched in molecules regulating intra-Golgi transport."Traffic 8:359-368(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Dysfunction of Golgi tethers, SNAREs, and SNAPs in monocrotaline-induced pulmonary hypertension."Am. J. Physiol. 292:L1526-L1542(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability."Exp. Cell Res. 317:2353-2363(2011) [PubMed] [Europe PMC] [Abstract]
  12. "GS28 protects neuronal cell death induced by hydrogen peroxide under glutathione-depleted condition."Korean J. Physiol. Pharmacol. 15:149-156(2011) [PubMed] [Europe PMC] [Abstract]
  13. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]