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Golgin A4 (GOLGA4)

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GCP2; GOLG; p230; Golgin-240; Golgi Autoantigen,Golgin Subfamily a, 4; 256 kDa golgin; Trans-Golgi p230; Golgin-245

Golgin A4 (GOLGA4)
CCC H994
HGNC 4427
MGI 1859646
PubMed 20085582
RGD 1591925
UniProt Q13439
Wiki GOLGA4
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The golgins are a family of proteins, of which the protein encoded by this gene is a member, that are localized to the Golgi.
Golgin A4 has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternative splice variants have been described but their full-length nature has not been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgin A4 (GOLGA4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgin A4 (GOLGA4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgin A4 (GOLGA4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgin A4 (GOLGA4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgin A4 (GOLGA4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgin A4 (GOLGA4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgin A4 (GOLGA4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgin A4 (GOLGA4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgin A4 (GOLGA4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgin A4 (GOLGA4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Golgin A4 (GOLGA4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Golgin A4 (GOLGA4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Golgin A4 (GOLGA4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Golgin A4 (GOLGA4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Golgin A4 (GOLGA4) ELISA Kit Customized Service Offer
  1. "Molecular characterization of trans-Golgi p230: a human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif."J. Biol. Chem. 271:8328-8337(1996) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular characterization of golgin-245, a novel Golgi complex protein containing a granin signature."J. Biol. Chem. 270:31262-31268(1995) [PubMed] [Europe PMC] [Abstract]
  4. Thesis (1994), Instituto municipal de investigacion medica, Spain
  5. "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins."J. Biol. Chem. 276:22826-22837(2001) [PubMed] [Europe PMC] [Abstract]
  6. "Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery."Exp. Cell Res. 298:388-398(2004) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus."Mol. Cell 12:863-874(2003) [PubMed] [Europe PMC] [Abstract]
  15. "Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1."Nat. Struct. Mol. Biol. 11:86-94(2004) [PubMed] [Europe PMC] [Abstract]