Testicular Fibrosis (TF)

The testicle or testis is the male gonad in animals. Like the ovaries to which they are homologous, the testicles are components of both the reproductive system and the endocrine system. The primary functions of the testes are to produce sperm and to produce androgens, primarily testosterone.

Model for Testicular fibrosis  was built with the classical method of establishing experimental autoimmune orchitis (EAO) combined with injecting Bacille Calmette-Guerin (BCG) into left testis. The incidence rate of EAO and the rate of testicular fibrosis were 100%, 11.1% and 100%, 81.5% at 80, 140 days after the first infection, respectively.