Calvarial Defects (CD)

Bone graft materials are commonly used to regenerate various bone defects (skull defects). For treatment of large bone defects challenging in orthopaedic clinics, bone graft substitutes are commonly used for the majority of surgeons. The reconstruction of cranial defects via facilitating bone regeneration can be a challenging task for craniofacial surgeons that result from trauma, congenital anomaly, or a pathological lesion requires surgical intervention. However, the limitations and clinical problems to autograft or allograft repair that serves as the most commonly used treatment strategy include allograft resorption, fracture and a limited supply of autografts .