Galactose-3-O-Sulfotransferase 1 (GAL3ST1)
[Edit]CST; Cerebroside Sulfotransferase; Galactosylceramide sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase
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Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. GAL3ST1 is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.
The GalCer sulfotransferase cDNA encodes a 423-amino acid protein with a predicted type II transmembrane topology and 2 potential N-linked glycosylation sites. GalCer sulfotransferase is not homologous to either the cytosolic sulfotransferases or the Golgi sulfotransferases.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPJ076Hu01 | Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAJ076Hu01 | Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | WB; ICC; IHC-P; IHC-F; ELISA. |
| Assay Kits | SEJ076Hu | ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | SEJ076Mu | ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPJ076Ra01 | Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAJ076Ra01 | Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | WB; IHC; ICC; IP. |
| Assay Kits | n/a | CLIA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) | ELISA Kit Customized Service Offer |
- "Molecular cloning and expression of cDNA encoding human 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase."J. Biol. Chem. 272:4864-4868(1997) [PubMed] [Europe PMC] [Abstract]
- "Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene."Eur. J. Biochem. 267:2672-2679(2000) [PubMed] [Europe PMC] [Abstract]
- "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells."J. Biochem. 119:421-427(1996) [PubMed] [Europe PMC] [Abstract]