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Glucose-6-Phosphatase, Catalytic (G6PC)

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G6PT; GSD1a; Glycogen Storage Disease Type I,von Gierke Disease; Glucose-6-phosphatase alpha

Glucose-6-Phosphatase, Catalytic (G6PC)
CCC J081
HGNC 4056
MGI 95607
PubMed 18449899
RGD 2644
UniProt P35575
Wiki G6PC
The basic defect resides in glucose-6-phosphatase. The liver and kidney are involved, and hypoglycemia is a major problem. Lipidemia also occurs and may lead to xanthoma formation. Survival to adulthood, previously rare, is now the usual situation. Hyperuricemia has been observed in a considerable number of patients and in some clinical gout has occurred. Inhibited tubular secretion of uric acid due to hyperlactic acidemia and ketonemia, and overproduction of uric acid have been postulated. the effects of glycerol administered by mouth on levels of glucose and of lactate, together with the response to epinephrine or glucagon, permitted differentiation of the several types of hepatic glycogenosis (I, II, III and IV). The glycogen storage diseases are notable examples of genetic heterogeneity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ081Hu01 Recombinant Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
RPJ081Hu02 Recombinant Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAJ081Hu21 Monoclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
PAJ081Hu01 Polyclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
PAJ081Hu02 Polyclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
Assay Kits SEJ081Hu ELISA Kit for Glucose-6-Phosphatase, Catalytic (G6PC) Enzyme-linked immunosorbent assay for Antigen Detection.
SCJ081Hu CLIA Kit for Glucose-6-Phosphatase, Catalytic (G6PC) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ081Mu01 Recombinant Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
RPJ081Mu02 Recombinant Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
EPJ081Mu41 Eukaryotic Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ081Mu01 Polyclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
PAJ081Mu02 Polyclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
Assay Kits SEJ081Mu ELISA Kit for Glucose-6-Phosphatase, Catalytic (G6PC) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ081Ra01 Recombinant Glucose-6-Phosphatase, Catalytic (G6PC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ081Ra01 Polyclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
MAJ081Ra21 Monoclonal Antibody to Glucose-6-Phosphatase, Catalytic (G6PC) WB; IHC; ICC; IP.
Assay Kits SEJ081Ra ELISA Kit for Glucose-6-Phosphatase, Catalytic (G6PC) Enzyme-linked immunosorbent assay for Antigen Detection.
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