Fucokinase belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.The deduced 990-amino acid FUK protein has a predicted molecular mass of 107 kD. It contains 5 C-terminal motifs characteristic of the ATP-binding sites of hexokinases, as well as 31 potential phosphorylation sites evenly distributed throughout its sequence.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Fucokinase (FUK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Fucokinase (FUK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fucokinase (FUK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fucokinase (FUK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fucokinase (FUK) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Fucokinase (FUK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Fucokinase (FUK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fucokinase (FUK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fucokinase (FUK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fucokinase (FUK) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Fucokinase (FUK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Fucokinase (FUK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Fucokinase (FUK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Fucokinase (FUK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Fucokinase (FUK) | ELISA Kit Customized Service Offer |
- "Identification of human L-fucose kinase amino acid sequence."Biochem. Biophys. Res. Commun. 294:650-654(2002) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]