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Emerin (EMD)

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EDMD; STA; LEMD5; Emery-Dreifuss Muscular Dystrophy; LEM Domain Containing 5

Emerin (EMD)
CCC J163
HGNC 3331
MGI 108117
PubMed 17536044
RGD 2551
UniProt P50402
Wiki Emerin
Emerin, together with MAN1, is a LEM domain-containing integral membrane protein of the nuclear membrane in vertebrates. The function of MAN1 is not extensively known, but emerin is known to interact with nuclear lamins, barrier-to-autointegration factor (BAF), nesprin-1alpha , and a transcription repressor.
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. Mutations in emerin cause X-linked recessive Emery-Dreifuss muscular dystrophy.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Emerin (EMD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Emerin (EMD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Emerin (EMD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Emerin (EMD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Emerin (EMD) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Emerin (EMD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Emerin (EMD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Emerin (EMD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Emerin (EMD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Emerin (EMD) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Emerin (EMD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Emerin (EMD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Emerin (EMD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Emerin (EMD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Emerin (EMD) ELISA Kit Customized Service Offer
  1. "Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy."Nat. Genet. 8:323-327(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci."Hum. Mol. Genet. 5:659-668(1996) [PubMed] [Europe PMC] [Abstract]
  3. "A novel emerin mutation in a Japanese patient with Emery-Dreifuss muscular dystrophy."Hum. Genet. 97:693-694(1996) [PubMed] [Europe PMC] [Abstract]
  4. "Identification of new mutations in the Emery-Dreifuss muscular dystrophy gene and evidence for genetic heterogeneity of the disease."Hum. Mol. Genet. 4:1859-1863(1995) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]