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Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1)

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EUHMTASE1; GLP; KMT1D; Lysine N-methyltransferase 1D; Histone H3-K9 methyltransferase 5; G9a-like protein 1; Histone-lysine N-methyltransferase EHMT1

Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1)
CCC J174
HGNC 24650
MGI 1924933
PubMed 24196706
RGD 1307588
UniProt Q9H9B1
EHMT1 is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition.
The 1,267-amino acid EU-HMTase-1 protein contains ankyrin repeats and a SET domain. EU-HMTase-1 shares 63% sequence similarity with NG36/G9A. EU-HMTase-1 exhibited histone methyltransferase activity with a specificity for histone H3 in core histones, whereas it hardly methylated nucleosomes, suggesting that other subunits in the E2F6 complex are required for modification of nucleosomal substrates.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Euchromatic Histone Lysine-N-Methyltransferase 1 (EHMT1) ELISA Kit Customized Service Offer
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