Dysferlin Interacting Protein 1 (DYSFIP1)
[Edit]PPP1R27; Toonin; Protein phosphatase 1 regulatory subunit 27
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DYSFIP1is a 154 amino acid protein containing two ankyrin (ANK) repeats, which are L-shaped structures containing one β-hairpin and two α-helices that may located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.Two key tumor suppressor genes are associated with chromosome 17, namely,p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon,prostate gland and fallopian tubes.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dysferlin Interacting Protein 1 (DYSFIP1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dysferlin Interacting Protein 1 (DYSFIP1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Dysferlin Interacting Protein 1 (DYSFIP1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Dysferlin Interacting Protein 1 (DYSFIP1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Dysferlin Interacting Protein 1 (DYSFIP1) | ELISA Kit Customized Service Offer |
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Docking motif-guided mapping of the interactome of protein phosphatase-1."Chem. Biol. 16:365-371(2009) [PubMed] [Europe PMC] [Abstract]