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Dynein, Axonemal, Heavy Chain 3 (DNAH3)

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Dnahc3b; DLP3; Hsadhc3; Ciliary dynein heavy chain 3; Axonemal beta dynein heavy chain 3

Dynein, Axonemal, Heavy Chain 3 (DNAH3)
CCC J203
HGNC 2949
MGI 2683040
PubMed 23663090
RGD 1305855
UniProt Q8TD57
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets.
Chapelin et al. (1997) isolated partial cDNAs encoding a dynein heavy chain (DHC), DNAH3, which they designated DNAHC3B. By sequence analysis, they determined that DNAH3 belongs to the putative axonemal inner dynein arm DHC group and is homologous to rat DLP3. RT-PCR analysis indicated that DNAH3 is expressed primarily in trachea and testis, 2 tissues containing axonemal structures.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dynein, Axonemal, Heavy Chain 3 (DNAH3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dynein, Axonemal, Heavy Chain 3 (DNAH3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dynein, Axonemal, Heavy Chain 3 (DNAH3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dynein, Axonemal, Heavy Chain 3 (DNAH3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dynein, Axonemal, Heavy Chain 3 (DNAH3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene."Gene 200:193-202(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment."FEBS Lett. 412:325-330(1997) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."Genomics 60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
  7. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]