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Cleavage Stimulation Factor 2 (CSTF2)

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CstF-64; •Cleavage stimulation factor 64 kDa subunit

Cleavage Stimulation Factor 2 (CSTF2)
CCC J320
HGNC 2484
MGI 1343054
PubMed 16769980
UniProt P33240
Wiki CSTF2
CSTF2encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
Polyadenylation of mRNA is a complex process that requires multiple protein factors, including 3 cleavage stimulation factors (CSTF1; CSFT2, and CSTF3). CstF2, a 64-kD protein, contains a ribonucleoprotein (RNP)-type RNA binding domain in the N-terminal region . The CstF2 protein expressed in E. coli can be cross-linked to RNAs containing polyadenylation signal sequences (AAUAAA).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cleavage Stimulation Factor 2 (CSTF2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cleavage Stimulation Factor 2 (CSTF2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cleavage Stimulation Factor 2 (CSTF2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cleavage Stimulation Factor 2 (CSTF2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cleavage Stimulation Factor 2 (CSTF2) ELISA Kit Customized Service Offer
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