CORO1C encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.
Sequence analysis predicted that the 474-amino acid CORO1C protein is 65% identical to CORO1A, 45% identical to CORO2B, and 97% identical to mouse coronin-3. CORO1C contains 5 N-terminal trp-asp (WD) repeats and a C-terminal coiled-coil motif. Northern blot and RT-PCR analysis detected a major 4.0-kb CORO1C transcript as well as 2 minor transcripts; no splice variants were detected, however, suggesting the presence of some cross-hybridizing gene(s).
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Coronin 1C (CORO1C) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Coronin 1C (CORO1C) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Coronin 1C (CORO1C) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Coronin 1C (CORO1C) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coronin 1C (CORO1C) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Coronin 1C (CORO1C) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Coronin 1C (CORO1C) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Coronin 1C (CORO1C) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Coronin 1C (CORO1C) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coronin 1C (CORO1C) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Coronin 1C (CORO1C) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Coronin 1C (CORO1C) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Coronin 1C (CORO1C) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Coronin 1C (CORO1C) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coronin 1C (CORO1C) | ELISA Kit Customized Service Offer |
- "Isolation and chromosomal assignment of a novel human gene, CORO1C, homologous to coronin-like actin-binding proteins."Cytogenet. Cell Genet. 88:221-224(2000) [PubMed] [Europe PMC] [Abstract]
- "Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle."J. Mol. Biol. 393:287-299(2009) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus."J. Biol. Chem. 277:48858-48867(2002) [PubMed] [Europe PMC] [Abstract]
- "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]